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Presentations on Bump Alleviative Fields awning a ample and growing ambit of topics, with about 80 percent of presentations able by alien authors

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ST. HELIER, Jersey–(BUSINESS WIRE)–#btsm–Novocure (NASDAQ: NVCR) today appear 43 presentations on Bump Alleviative Fields, including three articulate presentations, will be featured at the 24th Annual Meeting of the Society for Neuro-Oncology (SNO) on Nov. 20 through Nov. 24 in Phoenix. Presentations on Bump Alleviative Fields awning a ample and growing ambit of topics. Alien authors able 34 of the 43 presentations.

The articulate presentations on Bump Alleviative Fields accommodate an EF-14 column hoc subgroup assay on bump advance rates, and the pilot abstraction after-effects of Bump Alleviative Fields accumulated with radiotherapy and temozolomide for the assay of anew diagnosed glioblastoma.

Highlights amid affiche presentations accommodate the combinations of Bump Alleviative Fields with added therapies such as radiation and immunotherapies, simulations, bloom economics and outcomes research, accommodating advocacy, and assay on the apparatus of action.

“Year afterwards year, it is amazing to see the connected focus on Bump Alleviative Fields at the SNO Annual Meeting,” said Novocure CEO Asaf Danziger. “From our aboriginal presentation at SNO in 2008 to today, added than 250 abstracts on Bump Alleviative Fields accept been included at one of the best important conferences in neuro-oncology worldwide. I am appreciative of our aggregation for their adamant focus on avant-garde assay and for their constant drive in adopting acquaintance of our assay amid the authentic community. We attending avant-garde to accession advantageous year at SNO.”

(Abstract #: ACTR-46) Bump Alleviative Fields accumulated with radiotherapy and temozolomide for the assay of anew diagnosed glioblastoma: Final after-effects from a pilot study. R. Grossman. 2:45 to 2:50 p.m. MST Nov. 22.

(Abstract #: RTHP-28) TTFields assay affects bump advance rates: A post-hoc assay of the cardinal appearance 3 EF-14 trial. Z. Bomzon. 4:05 to 4:10 p.m. MST Nov. 22.

(Abstract #: QOLP-24) Patients’/parents’ adventures of accepting Optune delivered bump assay fields: A Pediatric Academician Bump Consortium Study: PBTC-048. J. Lai. 7:50 to 7:54 p.m. MST Nov. 22.

(Abstract #: RDNA-10) TTFields assay planning for targeting assorted lesions advance throughout the brain. Z. Bomzon. 7:30 to 9:30 p.m. MST Nov. 22. (Radiation Biology and DNA Repair/Basic Science)

(Abstract #: NIMG-20) Evaluation of arch assay affection for assay planning of bump alleviative fields in academician tumors. Z. Bomzon. 7:30 to 9:30 p.m. MST Nov. 22. (Neuro-Imaging/Clinical Research)

(Abstract #: HOUT-24) Challenges and successes in the all-around agreement of a advance medical technology for assay of glioblastoma multiforme. C. Proescholdt. 7:30 to 9:30 p.m. MST Nov. 22. (Health Outcome Measures/Clinical Research)

(Abstract #: EXTH-02) The claret academician barrier (BBB) permeability is adapted by Bump Alleviative Fields (TTFields) in vivo. E. Schulz. 7:30 to 9:30 p.m. MST Nov. 22. (Experimental Therapeutics/Basic Science)

(Abstract #: IMMU-06) TTFields induces immunogenic corpuscle afterlife and STING alleyway activation through cytoplasmic double-stranded DNA in glioblastoma cells. D. Chen. 7:30 to 9:30 p.m. MST Nov. 22. (Immunology/Basic Science)

(Abstract #: DRES-06) Prostaglandin E Receptor 3 mediates attrition to Bump Alleviative Fields in glioblastoma cells. D. Chen. 7:30 to 9:30 p.m. MST Nov. 22. (Drug Resistance/Basic Science)

(Abstract #: EXTH-34) In vitro bump alleviative fields (TTFields) activated above-mentioned to radiation enhances the acknowledgment to radiation in patient-derived glioblastoma corpuscle lines. S. Mittal. 7:30 to 9:30 p.m. MST Nov. 22. (Experimental Therapeutics/Basic Science)

(Abstract #: CSIG-20) Effect of tumor-treating fıelds (TTFields) on EGFR phosphorylation in GBM corpuscle lines. M. Reinert. 7:30 to 9:30 p.m. MST Nov. 22. (Cell Signaling and Signaling Pathways/Basic Science)

(Abstract #: CBMT-14) The dielectric backdrop of academician bump tissue. M. Proescholdt. 7:30 to 9:30 p.m. MST Nov. 22. (Cell Biology and Metabolism/Basic Science)

(Abstract #: CSIG-26) Is built-in apoptosis the signaling alleyway activated by tumor-treating fields for glioblastoma. K. Carlson. 7:30 to 9:30 p.m. MST Nov. 22. (Cell Signaling and Signaling Pathways/Basic Science)

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(Abstract #: ATIM-08) Balloon in Progress: CA209-9Y8 appearance 2 balloon of bump alleviative fields (TTFs), nivolumab plus/minus ipilimumab for bevacizumab-naïve, alternate glioblastoma. Y. Odia. 7:30 to 9:30 p.m. MST Nov. 22. (Adult Analytic Trials – Immunologic/Clinical Research)

(Abstract #: ACTR-60) A appearance 2, historically controlled abstraction testing the ability of TTFields with accessory temozolomide in high-risk WHO brand II and III astrocytomas (FORWARD). A. Allen. 7:30 to 9:30 p.m. MST Nov. 22. (Adult Analytic Trials – Non-Immunologic/Clinical Research)

(Abstract #: TMIC-54) Comparison of cellular appearance at dissection in glioblastoma patients with accepted assay of affliction and bump assay fields. A. Lowman. 7:30 to 9:30 p.m. MST Nov. 22. (Tumor Microenvironment/Basic Science)

(Abstract #: ACTR-26) Assurance and ability of bevacizumab added Bump Alleviative Fields (TTFields) in patients with alternate glioblastoma (GBM): abstracts from a appearance II analytic trial. J. Fallah. 7:30 to 9:30 p.m. MST Nov. 22. (Adult Analytic Trials – Non-immunologic/Clinical Research)

(Abstract #: RBTT-02) Radiosurgery followed by Bump Alleviative Fields for academician metastases (1-10) from NSCLC in the appearance 3 METIS trial. V. Gondi. 7:30 to 9:30 p.m. MST Nov. 22. (Randomized Academician Bump Trials in Development/Clinical Research)

(Abstract #: INNV-16) Complete acknowledgment of thalamic IDH wildtype glioblastoma afterwards proton assay followed by chemotherapy calm with Bump Alleviative Fields. M. Stein. 7:30 to 9:30 p.m. MST Nov. 22. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: INNV-20) A analytical assay of bump alleviative fields assay for primary for alternate and glioblastoma. P. Shah. 7:30 to 9:30 p.m. MST Nov. 22. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: STEM-16) Dual Inhibition of Protein Arginine Methyltransferase 5 and Protein Phosphatase 2a Enhances the Anti-tumor Ability in Primary Glioblastoma Neurospheres. H. Sur. 7:30 to 9:30 p.m. MST Nov. 22. (Stem Cells/Basic Science)

(Abstract #: CBMT-13) 3DEP arrangement to assay the electrical backdrop of altered corpuscle curve as predictive markers of optimal bump alleviative fields (TTFields) abundance and sensitivity. M. Giladi. 5 to 7 p.m. MST Nov. 23. (Cell Biology and Metabolism/Basic Science)

(Abstract #: EXTH-37) A atypical transducer arrangement blueprint for accustomed Bump Alleviative Fields to the spine. Z. Bomzon. 5 to 7 p.m. MST Nov. 23. (Experimental Therapeutics/Basic Science)

(Abstract #: NIMG-41) Rapid and authentic conception of patient-specific computational models for GBM patients accepting Optune assay with accepted imaging (T1w/PD). Z. Bomzon. 5 to 7 p.m. MST Nov. 23. (Neuro-Imaging/Clinical Research)

(Abstract #: HOUT-17) Utilities of attenuate cancers like cancerous pleural mesothelioma and glioblastoma multiforme – do they compare? C. Proescholdt. 5 to 7 p.m. MST Nov. 23. (Health Outcome Measures/Clinical Research)

(Abstract #: INNV-17) Avant-garde educational approaches to enhance accommodating and caregiver compassionate of Optune® for glioblastoma. M. Shackelford. 5 to 7 p.m. MST Nov. 23. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: EXTH-05) Therapeutic implications of TTFields induced DNA accident and archetype accent in atypical combinations for blight treatment. N. Karanam. 5 to 7 p.m. MST Nov. 23. (Experimental Therapeutics/Basic Science)

(Abstract #: EXTH-31) Aggregate of bump alleviative fields (TTFields) and paclitaxel produces accretion reductions in admeasurement and clonogenicity in patient-derived metastatic non-small corpuscle lung blight (NSCLC) cells. S. Michelhaugh. 5 to 7 p.m. MST Nov. 23 (Experimental Therapeutics/Basic Science)

(Abstract #: EXTH-53) Bump Alleviative Fields leads to changes in film permeability and added assimilation by anti-glioma drugs. E. Chang. 5 to 7 p.m. MST Nov. 23. (Experimental Therapeutics/Basic Science)

(Abstract #: RDNA-01) Tubulin and microtubules as atomic targets for TTField therapy. J. Tuszynski. 5 to 7 p.m. MST Nov. 23. (Radiation Biology and DNA Repair/Basic Science)

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(Abstract #: SURG-01) OptimalTTF-1: Final after-effects of a appearance 1 study: Aboriginal glioblastoma ceremony analytical targeted skull adjustment anaplasty to enhance Bump Alleviative Fields strength. A. Korshoej. 5 to 7 p.m. MST Nov. 23. (Surgical Therapy/Clinical Research)

(Abstract #: ATIM-39) Appearance 2 open-labeled abstraction of accessory temozolomide added Bump Alleviative Fields added Pembrolizumab in patients with anew diagnosed glioblastoma (2-THE-TOP). D. Tran. 5 to 7 p.m. MST Nov. 23. (Adult Analytic Trials – Immunologic/Clinical Research)

(Abstract #: ACTR-49) Initial acquaintance with attic canning and radiation added circumstantial alternating electric tumor-treating fields (SPARE) for glioblastoma patients. A. Song. 5 to 7 p.m. MST Nov. 23. (Adult Analytic Trials – Non-Immunologic/Clinical Research)

(Abstract #: RTHP-25) TTFields dosage administration alters bump advance patterns: An imaging-based assay of the randomized appearance 3 EF-14 trial. M. Ballo. 5 to 7 p.m. MST Nov. 23. (Radiation Therapy/Clinical Research)

(Abstract #: ACTR-19) Address on the aggregate of Axitinib and Bump Alleviative Fields (TTFields) in three patients with alternate glioblastoma. E. Schulz. 5 to 7 p.m. MST Nov. 23. (Adult Analytic Trials – Non-Immunologic/Clinical Research)

(Abstract #: PATH-47) TTF may administer careful burden to glioblastoma clones with aneuploidy: a case report. M. Ruff. 5 to 7 p.m. MST Nov. 23. (Molecular Pathology and Classification – Developed and Pediatric/Clinical Research)

(Abstract #: RARE-39) Aggregate of Bump Alleviative Fields (TTFields) with lomustine (CCNU) and temozolomide (TMZ) in anew diagnosed glioblastoma (GBM) patients – a bi-centric analysis. L. Lazaridis. 5 to 7 p.m. MST Nov. 23. (Rare Tumors/Clinical Research)

(Abstract #: ACTR-31) The use of TTFields for anew diagnosed GBM patients in Germany in accepted analytic affliction (TIGER: TTFields in Germany in accepted analytic care). O. Bahr. 5 to 7 p.m. MST Nov. 23. (Adult Analytic Trials – Non-Immunologic/Clinical Research)

(Abstract #: INNV-09) Analytic ability of bump alleviative fields for anew diagnosed glioblastoma. Y. Liu. 5 to 7 p.m. MST Nov. 23. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: EXTH-61) Celecoxib Improves Outcome of Patients Advised with Bump Alleviative Fields. K. Swanson. 5 to 7 p.m. MST Nov. 23. (Experimental Therapeutics/Basic Science)

(Abstract #: INNV-23) Glioblastoma and Facebook: An Assay Of Perceived Etiologies and Treatments. N. Reddy. 5 to 7 p.m. MST Nov. 23. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: INNV-12) Outcomes in a Real-world Practice For Patients With Primary Glioblastoma: Impact of a Specialized Neuro-oncology Blight Affliction Program. N. Banerji. 5 to 7 p.m. MST Nov. 23. (Innovations in Accommodating Care/Clinical Research)

(Abstract #: RBTT-11): NRG Oncology NRG-BN006: A Appearance II/III Randomized, Open-label Abstraction of Toca 511 and Toca FC With Accepted of Affliction Compared to Accepted of Affliction in Patients With Anew Diagnosed Glioblastoma. M. Ahluwalia. 5 to 7 p.m. MST Nov. 23. (Randomized Academician Bump Trials Development/Clinical Research)

Novocure is a all-around oncology aggregation alive to extend adaptation in some of the best advancing forms of blight through the development and commercialization of its avant-garde therapy, Bump Alleviative Fields. Bump Alleviative Fields is a blight assay that uses electric fields acquainted to specific frequencies to agitate solid bump blight corpuscle division. Novocure’s commercialized articles are accustomed for the assay of developed patients with glioblastoma and cancerous pleural mesothelioma. Novocure has advancing or completed analytic trials investigating Bump Alleviative Fields in academician metastases, non-small corpuscle lung cancer, pancreatic cancer, ovarian blight and alarmist cancer.

Headquartered in Jersey, Novocure has U.S. operations in Portsmouth, New Hampshire, Malvern, Pennsylvania and New York City. Additionally, the aggregation has offices in Germany, Switzerland, Japan and Israel. For added advice about the company, amuse appointment www.novocure.com or chase us at www.twitter.com/novocure.

Optune is advised as a assay for developed patients (22 years of age or older) with histologically-confirmed glioblastoma multiforme (GBM).

Optune with temozolomide is adumbrated for the assay of developed patients with anew diagnosed, supratentorial glioblastoma afterward acute debulking surgery, and achievement of radiation assay calm with accessory accepted of affliction chemotherapy.

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For the assay of alternate GBM, Optune is adumbrated afterward histologically- or radiologically-confirmed ceremony in the supratentorial arena of the academician afterwards accepting chemotherapy. The accessory is advised to be acclimated as a monotherapy, and is advised as an another to accepted medical assay for GBM afterwards surgical and radiation options accept been exhausted.

The NovoTTF-100L Arrangement is adumbrated for the assay of developed patients with unresectable, locally avant-garde or metastatic, cancerous mesothelioma (MPM) to be acclimated accordingly with pemetrexed and platinum-based chemotherapy.

Important Assurance Information

Do not use Optune in patients with GBM with an built-in medical device, a skull birthmark (such as, missing cartilage with no replacement), or ammo fragments. Use of Optune calm with skull defects or ammo bits has not been activated and may possibly advance to tissue accident or cede Optune ineffective. Do not use the NovoTTF-100L Arrangement in patients with MPM with implantable cyberbanking medical accessories such as pacemakers or implantable automated defibrillators, etc.

Use of Optune for GBM or the NovoTTF-100L Arrangement for MPM calm with built-in cyberbanking accessories has not been activated and may advance to adulterated of the built-in device.

Do not use Optune for GBM or the NovoTTF-100L Arrangement for MPM in patients accepted to be acute to conductive hydrogels. Bark acquaintance with the gel acclimated with Optune and the NovoTTF-100L Arrangement may frequently account added bloom and itching, and may rarely advance to astringent allergic reactions such as shock and respiratory failure.

Optune and the NovoTTF-100L Arrangement can abandoned be assigned by a healthcare provider that has completed the appropriate acceptance training provided by Novocure®.

The best accepted (≥10%) adverse contest involving Optune in aggregate with chemotherapy in patients with GBM were thrombocytopenia, nausea, constipation, vomiting, fatigue, convulsions, and depression.

The best accepted (≥10%) adverse contest accompanying to Optune assay abandoned in patients with GBM were medical accessory armpit acknowledgment and headache. Added below accepted adverse reactions were malaise, beef twitching, and avalanche accompanying to accustomed the device.

The best accepted (≥10%) adverse contest involving the NovoTTF-100L Arrangement in aggregate with chemotherapy in patients with MPM were anemia, constipation, nausea, asthenia, chest pain, fatigue, accessory bark reaction, pruritus, and cough.

Other abeyant adverse furnishings associated with the use of the NovoTTF-100L Arrangement include: assay accompanying bark toxicity, allergic acknowledgment to the adhesive or to the gel, electrode overheating arch to affliction and/or bounded bark burns, infections at sites of electrode acquaintance with the skin, bounded amore and amazing awareness below the electrodes, beef twitching, medical armpit acknowledgment and bark breakdown/skin ulcer.

If the accommodating has an basal austere bark action on the advised area, appraise whether this may anticipate or briefly baffle with Optune and the NovoTTF-100L Arrangement treatment.

Do not appoint Optune or the NovoTTF-100L Arrangement for patients that are pregnant, you anticipate ability be abundant or are aggravating to get pregnant, as the assurance and capability of Optune and the NovoTTF-100L Arrangement in these populations accept not been established.

Forward-Looking Statements

In accession to actual facts or statements of accepted condition, this columnist absolution may accommodate advanced statements. Advanced statements accommodate Novocure’s accepted expectations or forecasts of approaching events. These may accommodate statements apropos advancing authentic advance on its assay programs, analytic balloon progress, development of abeyant products, estimation of analytic results, affairs for authoritative approval, accomplishment development and capabilities, bazaar affairs for its products, coverage, collections from third-party payers and added statements apropos affairs that are not actual facts. You may analyze some of these advanced statements by the use of words in the statements such as “anticipate,” “estimate,” “expect,” “project,” “intend,” “plan,” “believe” or added words and agreement of agnate meaning. Novocure’s achievement and banking after-effects could alter materially from those reflected in these advanced statements due to accepted financial, economic, authoritative and political altitude as able-bodied as added specific risks and uncertainties adverse Novocure such as those set alternating in its Quarterly Address on Form 10-Q filed on July 25, 2019, with the U.S. Securities and Exchange Commission. Given these risks and uncertainties, any or all of these advanced statements may prove to be incorrect. Therefore, you should not await on any such factors or advanced statements. Furthermore, Novocure does not intend to amend about any advanced statement, except as appropriate by law. Any advanced statements herein allege abandoned as of the date hereof. The Private Securities Litigation Reform Act of 1995 permits this discussion.

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